If you are a PAH researcher interested in obtaining a cohort of patient samples and/or data, this page will provide information on our procedure to request samples from the PAH Biobank. We bank biological specimens, generate genetic data, and collect clinical data.

The biological samples available for request may include: RNA, DNA, EBV lymphocyte cell lines, cDNA, plasma and serum. The genetic data available for request includes SNP genotype data (generated by Illumina’s Omni5 platform), coding sequence data for the following genes: BMPR2, ALK1, ENG, KCNK3, SMAD9, CAV1, and EIF2AK4 and dosage data for the following genes: BMPR2, ALK1 and ENG.

Clinical data includes medical history related to PAH such as PAH subtype, initial symptoms leading to diagnosis, comorbid conditions, PAH medications and concomitant medications.

Request Procedure

The procedures for requesting samples/data can be viewed through our request form. After submitting a formal request, the PAH Biobank Sample Proposal Review Committee will review the validity of the request before distributing any samples or data.  

To request more information about the samples/data at the PAH biobank before submitting a formal request, please email pahbiobank@cchmc.org with your name, institution, and a brief description of how our samples/data may be able to further your PAH research.